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The hexagonal structure of their honeycomb seemed like the optimal way to partition two-dimensional space into cells of equal area and minimal perimeter — allowing the insects to cut down on how much wax they needed to produce, and to spend less time and energy building ... How Cold Affects the Brain | The Scientist Magazine® My Account. My Folders. Individual subscribers or registered users accessing the site through an institutional site license can use this electronic filing cabinet to organize information available on Science journals. View Folders. E-Mail Alerts. Science offers a variety of alerts to registered users and subscribers. Even a 2°C drop in the core body temperature can cause hypothermia. At this point, the effects of cold on the brain are most apparent. "At 18°C, we'll have a massive leak in our blood-brain barrier, and the brain is not protected anymore from the normal junk we produce," Gracheva said. The resulting flood of toxins through the hole-ridden ... 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